Detailed Product Description

Original plant:Lycoris radiata herb

Specification: 98%,99%

Test Method:HPLC

Molecular Formula: C₁₇H₂₁NO₃HBr

Molecular Weight: 368.27

CAS No: 1953-04-4
Melting Point : 258~264
Solubility:Soluble in water,and slightly in alcohol.

Description:Galanthamine is an effective,competitive and reversible acetylcholine esterase inhibitor,especially used in curing lightly and moderate Alzheimer's Disease.

Biological effects:

Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.

Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.

Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type